Vaccinations and Malaria Prophylaxis for travellers to North America & the Caribbean
Please select the country.
anti-malarial drug regimens can be found below the main tables
|
|
Yellow Fever |
|
|
Hepatitis A |
|
|
Typhoid |
|
|
Tetanus |
|
|
Polio |
|
|
Meningitis |
|
|
Jap. B Encephalitis |
|
DIP
|
Diphtheria |
|
|
Rabies |
|
|
Hepatitis B |
|
M
|
Vaccination is mandatory and a certificate of vaccination is required for entry. |
|
C
|
A certificate of vaccination may be required if entering from an endemic country, (except for children <1 year old). |
|
R
|
Vaccination is recommended for the country but no evidence is required for entry. |
|
L
|
Long Term. Vaccination recommended for travellers staying in endemic areas for 3 months or more. Except Japanese B Encephalitis <1 month. |
|
MALARIA
REGIMEN |
YEL
|
HEP
A |
TYP
|
TET
|
POL
|
MEN
|
ENC
|
DIP
|
RAB
|
HEP
B |
|
| Anguilla No malaria risk |
-
|
C
|
R
|
R
|
R
|
R
|
-
|
-
|
-
|
-
|
-
|
|
| Antigua & Barbuda No malaria risk |
-
|
-
|
R
|
R
|
R
|
R
|
-
|
-
|
-
|
-
|
-
|
|
| Aruba No malaria risk |
-
|
C
|
R
|
R
|
R
|
R
|
-
|
-
|
-
|
-
|
-
|
|
| Bahamas No malaria risk |
-
|
-
|
R
|
R
|
R
|
R
|
-
|
-
|
-
|
-
|
-
|
|
| Barbados No malaria risk |
-
|
-
|
R
|
R
|
R
|
R
|
-
|
-
|
-
|
-
|
-
|
|
| Canada No malaria risk |
-
|
-
|
-
|
-
|
R
|
-
|
-
|
-
|
-
|
-
|
-
|
|
| Cayman Islands No malaria risk |
-
|
-
|
R
|
R
|
R
|
R
|
-
|
-
|
-
|
-
|
-
|
|
| Cuba No malaria risk |
-
|
-
|
R
|
R
|
R
|
R
|
-
|
-
|
-
|
-
|
-
|
|
| Dominica No malaria risk |
-
|
-
|
R
|
R
|
R
|
R
|
-
|
-
|
-
|
-
|
-
|
|
MALARIA
REGIMEN |
YEL
|
HEP
A |
TYP
|
TET
|
POL
|
MEN
|
ENC
|
DIP
|
RAB
|
HEP
B |
|
| Puerto
Rico No malaria risk |
-
|
-
|
R
|
R
|
R
|
R
|
-
|
-
|
-
|
-
|
-
|
|
| Saint
Kitts & Nevis No malaria risk |
-
|
C
|
R
|
R
|
R
|
R
|
-
|
-
|
-
|
-
|
-
|
|
| Saint Lucia No malaria risk |
-
|
C
|
R
|
R
|
R
|
R
|
-
|
-
|
-
|
-
|
-
|
|
| Saint Vincent & the Grenadines No malaria risk |
-
|
C
|
R
|
R
|
R
|
R
|
-
|
-
|
-
|
-
|
-
|
|
| Trinidad & Tobago No malaria risk |
-
|
RC
|
R
|
R
|
R
|
R
|
-
|
-
|
-
|
-
|
-
|
|
| Turks & Caicos No malaria risk |
-
|
C
|
R
|
R
|
R
|
R
|
-
|
-
|
-
|
-
|
-
|
|
| United States of America including Bermuda & Hawaii No malaria risk |
-
|
-
|
-
|
-
|
R
|
-
|
-
|
-
|
-
|
-
|
-
|
|
| Virgin Islands No malaria risk |
-
|
-
|
R
|
R
|
R
|
R
|
-
|
-
|
-
|
-
|
-
|
|
|
|
The information
supplied is derived from a number
of reliable sources and is compared
and compiled into the alphabetical
lists found on this web site. Countries requiring malaria prophylaxis should be regarded as being at risk all year round and you should also assume that the whole country is at risk unless otherwise indicated. The malaria regimen is the recommended regimen for a country. Use of the incorrect regimen may not provide adequate cover. When there are two different regimens for the same country, they are area specific. Read the text to find out which regimen is suitable for the area you require. Where regimen 1 is indicated there is Chloroquine resistance in that region and it is very likely to be the Falciparum malaria which is the most serious form of the disease. In this instance it is vitally important that travellers take adequate prophylaxis. Remember:- No prophylaxis is 100% effective but not taking anti-malarials where they are indicated will put you at greater risk should you get the disease. Remember - Malaria is a killer! |
|
The Different Drug Regimens
|
|
| Regimen 1 | Mefloquine one 250mg tablet
weekly. OR Doxycycline one 100mg capsule daily. OR Malarone one tablet daily. |
| Regimen 2 | Chloroquine 300mgweekly (2x150mg tablets). PLUS Proguanil 200mg daily (2x100mg tablets). |
| Regimen 3 | Chloroquine 300mg
weekly (2x150mg tablets) OR Proguanil 200mg daily (2x100mg tablets). |
| Regimen 4 | No prophylactic tablets required but anti mosquito measures should be strictly observed: Avoid mosquito bites by covering up with clothing such as long sleeves and long trousers especially after sunset, using insect repellents on exposed skin and, when necessary, sleeping under a mosquito net. |
| . | |
| Proguanil | 100mg tablets are supplied as Paludrine Tablets |
| Chloroquine | 150mg tablets are supplied as Nivaquine or Avloclor Tablets |
| Mefloquine | 250mg tablets are supplied as Lariam Tablets |
| Malarone | is a combination of Atovaquone 250mg and Proguanil 100mg |
|
Length of Prophylaxis
|
|
| Chloroquine, Proguanil & Maloprim | Start one week before travel, throughout your stay in an endemic area and continue for four weeks after return. |
| Mefloquine (Lariam) | Start two and a half weeks before travel, throughout your stay in an endemic area and continue for four weeks after return. |
| Doxycycline | Start two days before travel, throughout your stay in an endemic area and continue for four weeks after return. |
| Malarone | Start two days before travel, throughout your stay in an endemic area and continue for one week after return. |
|
Take
the tablets absolutely regularly,
preferably with or after a meal.
|
|
|
Long
Term Use of Anti-Malaria Drugs
|
|
| Chloroquine | May be taken for periods exceeding five years. |
| Paludrine | May be taken for periods exceeding five years. |
| Maloprim | Can be taken for periods up to one year. |
| Mefloquine | Can be taken for periods up to one year. |
| Doxycycline | Can be taken for periods up to six months. |
| Malarone | Can be used for travel periods up to one year. |
|
Compatibility of Anti-Malaria Drugs
|
||||||
|
Pregnancy
|
Breast
Feeding
|
Epilepsy
|
Psoriasis
|
Altitude
|
Scuba
Diving
|
|
| Chloroquine |
OK
|
OK
|
NO
|
NO
|
OK
|
OK
|
| Paludrine |
OK
|
OK
|
OK
|
OK
|
OK
|
OK
|
| Mefloquine |
OK*
|
NO
|
NO
|
OK
|
NO
|
NO
|
| Doxycycline |
NO
|
NO
|
OK
|
OK
|
OK
|
OK
|
| Malarone |
NO
|
NO
|
OK
|
OK
|
OK
|
OK
|
|
*
These drugs are not suitable during
the first trimester of pregnancy.
|
||||||
|
Childrens' Dosages:
Calculate the dose by weight rather than by age if possible |
|||||
|
Age/Weight
|
Chloroquine
(once weekly) |
Proguanil
(once daily) |
Mefloquine
(once weekly) |
Doxycycline
(once daily) |
Malarone
(once daily) |
|
0
- 12 weeks
under 6kg |
1/4
tablet
|
1/4
tablet
|
-
|
-
|
-
|
|
3
- 12 months
6 - 10kg |
1/2
tablet
|
1/2
tablet
|
1/4
tablet
|
-
|
-
|
|
1
- 3 years
10 - 16kg |
3/4
tablet
|
3/4
tablet
|
1/4
tablet
|
-
|
1
child's
tablet |
|
4
- 7 years
16 - 25kg |
1
tablet
|
1
tablet
|
1/2
tablet
|
-
|
1
child's
tablet |
|
8
- 12 years
25 - 45 Kg |
11/2
tablets
|
11/2
tablets
|
3/4
tablet
|
-
|
2
child's
tablets |
|
13
years and over
45kg and over |
2
tablets
|
2
tablets
|
1
tablet
|
1
capsule
|
1
adult
tablet |
|
The
above dosages are based upon the guidelines
issued by
the Advisory Committee on Malaria Prevention. |
|||||
|
Adult
Dosages
|
||
|
Regimen
|
Dose
for Chemoprophylaxis |
Usual
amount
per tablet (mg) |
| Areas without drug resistance: | ||
| Chloroquine Proguanil | 2 tablets weekly 2 tablets daily | 150mg (base) 100mg |
| Areas of little chloroquine resistance (poorly effective where marked resistance): | ||
| Chloroquine
plus Proguanil |
2
tablets weekly 2 tablets daily |
150mg
(base) 100mg |
| Areas of chloroquine resistant P. falciparum: | ||
|
Mefloquine
Doxycycline
Malarone (atovaquone & proguanil) |
1 tablet weekly 1 tablet/capsule daily 1 tablet daily |
250mg
(228 in USA)
100mg
250mg
atovaquone & 100mg proguanil |
Be Wise - Immunize!
Book your appointment calling 416.234.1987/88 or ONLINE




